TherOzone

TherOzone is a manufactuer of ozone related products which are used in dentistry.  Their website contains extensive links to various research on the subject, which are listed below.  You can also view the links directly on their website by clicking here.

Aqueous Ozone Research Related Presentations (pdf files)

Aqueous Ozone Related Research (PubMed)

Wound/Ulcer Treatment – Ozone (PubMed)

Sterilization and Disinfection – Ozone (PubMed)


Aqueous Ozone Research Related Presentations (pdf files)


Lynch E, Swift Jr EJ.  Evidence based efficacy of ozone for root canal irrigation. Ask the Experts (Publication of Department of Operative Dentistry, University of North Carolina) Journal Compilation. 2008;20(5): 287-293.
Dalton C. Therozone in Practice. Dentistry Clinical. Oct 2008: 29.
Julian K, Blackburn JC, Silwood CJ, Grootveld M.  Reduction of Microbial-Derived Components in Dental Unit Water Lines by Ozonated Water.   Restorative Dentistry and Gerodontology, School of Dentistry, Queen’s University Belfast, Northern Ireland. May 2007.
Domingo H, Silwood C, Blackburn J, Lynch E, Grootveld  M.  Oxidative Consumption Of Root Caries Biomolecules By Ozonated Water.  Queen’s University Belfast, Northern Ireland. May 2007.
Silwood CJ, Blackburn JC, Grootveld M.  Oxidative Modification Of Salivary Biomolecules with Therapeutic Ozonated Water.  IADR/AADR/CADR 85th General Session and Exhibition – Seq #232 – Salivary Analysis and Function 3:30 PM-4:45 PM, Friday, March 23, 2007 Ernest N. Morial Convention Center Exhibit Hall I2-J
Shenberg JE,  Blackburn JC, Silwood C, Lynch E, Grootveld M.  Ability Of Therapeutic Ozonated Water To Oxidatively Consume Orally-Active Biomolecules.  Restorative Dentistry And Gerodontology,  Queen’s University Belfast, Northern Ireland. May 2007.
Grootveld M, Blackburn JC, Silwood CJ, Lynch E.  Bleaching Components Responsible For Tooth Discoloration by Therapeutic Ozonated Water.  IADR/AADR/CADR 85th General Session and Exhibition – Seq #223 – Geriatric Dental Research
3:30 PM-4:45 PM, Friday, March 23, 2007 Ernest N. Morial Convention Center Exhibit Hall I2-J.

Aqueous Ozone Related Research

Noguchi F, Kitamura C, Nagayoshi M, Chen KK, Terashita M, Nishihara T. Ozonated water improves lipopolysaccharide-induced responses of an odontoblast-like cell line. J Endod. 2009 May;35(5):668-72. PubMed Abstract
Johansson E, Claesson R, van Dijken JW. Antibacterial effect of ozone on cariogenic bacterial species. J Dent. 2009 Jun;37(6):449-53. Epub 2009 Apr 1.  PubMed Abstract
Huth KC, Quirling M, Maier S, Kamereck K, Alkhayer M, Paschos E, Welsch U, Miethke T, Brand K, Hickel R. Effectiveness of ozone against endodontopathogenic microorganisms in a root canal biofilm model.  Int Endod J. 2009 Jan;42(1):3-13.  PubMed Abstract
Knight GM, McIntyre JM, Craig GG, Mulyani, Zilm PS. The inability of Streptococcus mutans and Lactobacillus acidophilus to form a biofilm in vitro on dentine pretreated with ozone. Aust Dent J. 2008 Dec;53(4):349-53. PubMed Abstract
Cardoso MG, de Oliveira LD, Koga-Ito CY, Jorge AO. Effectiveness of ozonated water on Candida albicans, Enterococcus faecalis, and endotoxins in root canals. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Mar;105(3):e85-91. PubMed Abstract
Lynch E. Evidence-based efficacy of ozone for root canal irrigation. J Esthet Restor Dent. 2008;20(5):287-93. PubMed Citation
Lynch E.  Oxidation of Biomolecules by Ozone. AADR 37th Annual Meeting and Exhibition .Seq #132 – Erosion, Molecular Biology, Clinical Studies – 2:45 PM-3:45 PM, Friday, April 4, 2008 Hilton Anatole Hotel Trinity I – Exhibit Hall.

Domingo H. Bleaching of Components Responsible for Tooth Discoloration by Ozone. AADR 37th Annual Meeting and Exhibition – Seq #117 – Pharmacology, Therapeutics & Toxicology Posters 1:30 PM-2:30 PM, Friday, April 4, 2008 Hilton Anatole Hotel Trinity I – Exhibit Hall.
Bocci VA.  Why orthodox medicine has not yet taken advantage of ozone therapy. Arch Med Res. 2008 Feb;39(2):259-60. Epub 2007 Nov 26. PubMed Citation
Bocci VA. The case for oxygen-ozonetherapy. Br J Biomed Sci. 2007;64(1):44-9. PubMed Citation
Bialka KL, Demirci A. Efficacy of aqueous ozone for the decontamination of Escherichia coli O157:H7 and Salmonella on raspberries and strawberries. J Food Prot. 2007 May;70(5):1088-92.  PubMed Abstract
Huth KC, Saugel B, Jakob FM, Cappello C, Quirling M, Paschos E, Ern K, Hickel R, Brand K. Effect of aqueous ozone on the NF-kappaB system. .J Dent Res. 2007 May;86(5):451-6.  PubMed Abstract
Estrela C, Estrela CR, Decurcio DA, Hollanda AC, Silva JA. Antimicrobial efficacy of ozonated water, gaseous ozone, sodium hypochlorite and chlorhexidine in infected human root canals. Int Endod J. 2007 Feb;40(2):85-93. PubMed Abstract
Agrillo A, Petrucci MT, Tedaldi M, Mustazza MC, Marino SM, Gallucci C, Iannetti G. New therapeutic protocol in the treatment of avascular necrosis of the jaws.  J Craniofac Surg. 2006 Nov;17(6):1080-3. PubMed Abstract
Huth KC, Jakob FM, Saugel B, Cappello C, Paschos E, Hollweck R, Hickel R, Brand K.  Effect of ozone on oral cells compared with established antimicrobials. Eur J Oral Sci. 2006 Oct;114(5):435-40. PubMed Abstract
Grootveld M, Silwood CJ, Lynch E.  High resolution 1H NMR investigations of the oxidative consumption of salivary biomolecules by ozone: relevance to the therapeutic applications of this agent in clinical dentistry. Biofactors. 2006;27(1-4):5-18.  PubMed Abstract
Stübinger S, Sader R, Filippi A.  The use of ozone in dentistry and maxillofacial surgery: a review.   Quintessence Int. 2006 May;37(5):353-9.  PubMed Abstract
Dodd MC, Buffle MO, Von Gunten U. Oxidation of antibacterial molecules by aqueous ozone: moiety-specific reaction kinetics and application to ozone-based wastewater treatment. Environ Sci Technol. 2006 Mar 15;40(6):1969-77.  PubMed Abstract
Baysan A, Lynch E. The use of ozone in dentistry and medicine. Part 2. Ozone and root caries. Prim Dent Care. 2006 Jan;13(1):37-41.  PubMed Abstract
Young JC, Zhu H, Zhou T. Degradation of trichothecene mycotoxins by aqueous ozone. Food Chem Toxicol. 2006 Mar;44(3):417-24. Epub 2005 Sep 23.  PubMed Abstract
Arita M, Nagayoshi M, Fukuizumi T, Okinaga T, Masumi S, Morikawa M, Kakinoki Y, Nishihara T. Microbicidal efficacy of ozonated water against Candida albicans adhering to acrylic denture plates. Oral Microbiol Immunol. 2005 Aug;20(4):206-10. PubMed Abstract

3 Responses to TherOzone

  1. the useful advises you presented do help the research for my group, thanks.

    - Lucas

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